March 15, 2026

E45 Psoriasis Cream

E45 Psoriasis Cream is a specially formulated emollient designed to soothe and moisturize dry, scaly skin associated with psoriasis. Unlike heavy steroid creams, it focuses on hydration and barrier repair. Many people turn to this cream for daily management of mild to moderate plaque psoriasis, as it helps reduce itching and flaking without strong active ingredients. But how effective is it really, and what are its specific uses? In this article, we explore everything you need to know about the product.

Uses of E45 Psoriasis Cream

E45 Psoriasis Cream is primarily used as a moisturizer and emollient for psoriasis-prone skin. Its key uses include:

  • Moisturizing dry skin: Psoriasis causes patches of thick, dry, and cracked skin. The cream helps restore moisture and softness.
  • Relieving itching: The cream's rich formula soothes irritation and reduces the urge to scratch.
  • Reducing flaking: By keeping skin hydrated, it minimizes scaling and flaking.
  • Supporting barrier function: Ingredients like urea and glycerin strengthen the skin's natural barrier.

Many users incorporate this cream into their daily skincare routine after bathing to lock in moisture. It is also safe to use on sensitive areas, such as the face and elbows, though a patch test is recommended. The cream is non-greasy and absorbs quickly, making it convenient for daytime use. However, for severe psoriasis flares, a stronger medicated treatment may be necessary. The cream is best suited for maintenance and prevention of flare-ups.

E45 Psoriasis Cream

Effectiveness of the Cream

Its effectiveness largely depends on the severity of the condition. While it is not a cure, it provides symptomatic relief for many. The cream contains urea (a humectant that helps shed dead skin) and glycerin, both known for their moisturizing properties. Clinical studies show that regular use of emollients like E45 can reduce itching and scaling in people with psoriasis by up to 50% over several weeks.

Key point: The cream is designed for daily moisturizing care. It does not contain steroids or coal tar, so it is safe for long-term use. For best results, apply it immediately after bathing when skin is still slightly damp.

User reviews often highlight improvements in skin texture and comfort within a week of consistent use. However, some find that during severe flares, the cream provides only temporary relief. It is important to manage expectations: it is an adjunct therapy, not a primary treatment for moderate to severe psoriasis. Many dermatologists recommend combining it with topical corticosteroids or phototherapy for better outcomes.

Warning: If you have open wounds, infected skin, or a known allergy to any ingredients (like urea or parabens), do not use E45 Psoriasis Cream without consulting a doctor. Discontinue use if you experience redness, burning, or irritation.

When comparing this cream to other emollients, its unique selling point is its mild formula that rarely causes adverse reactions. Brands like Cetaphil and Aveeno offer similar products, but E45 is often more affordable and widely available in the UK and Europe. To maximize benefits, apply the cream at least twice a day, focusing on affected areas. For stubborn scales, you can use it under occlusive gloves or clothing to enhance penetration.

In summary, this cream is a reliable moisturizer that helps manage psoriasis symptoms when used consistently. It is not a miracle cure, but it can significantly improve comfort and skin appearance. Always combine it with a comprehensive psoriasis management plan advised by your healthcare provider.